| Molecular Weight | 518.92 |
|---|---|
| Formula | C27H20ClFN4O4 |
| CAS No. | 1028486-01-2 |
| Storage | powder in solvent |
| Synonyms | N/A |
| Smiles | COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC |
mln8237 cas 1028486-01-2 Alisertib
$625.00
| Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. |
